jeebus @ mmw
+1y
You will get some good solid answers on this topic over at duallyscene.com , then can list you the facts of what you will and wont have to do.
You wont have any issues with wearing out parts any faster, they are a direct replacment for you, all you will need is some 8 to 10 lug adaptors, and wheels and tires. There are a lot of people that daily drive on the 22 or 24 combo. Allways go with a set of milled down wheels, never try to stretch your tire to fit on a 22.5 or 24.5 , there are people that do it, and have terrible outcome.
Taylor