I run Nitto 420S on my 22" wheels I have a 2003 Ford F150 Crewcab and of all the brands these have lasted the longest out of all others. The inside tread is made of harder rubber for less wear because of camber and the outter is softer for more grip cornering. I run the 285/40/22 so its not ballon tires but still has enough sidewall to help not curb check.