Real deal question!

I know this question has been asked several times! But I was wondering, if I put a 89 yota rearend in my isuzu would it bolt onto the drive line? If I have to change the driveshaft yoke how would I go about doing so, or do I just have to replace universal joints? Would the yota drive line go in it's place if I can get it? Just looking for some real answers before I do this so I know I do it right. I would like to get to know everything for the future before the site goes down. Thanks guys!

Im not sure about your truck exactly but what Im having to do with mine, chevy 350 being mated to a toyota supra rear differential is have a special drive shaft made that has the chevy splined part for the trans and the supra yoke patter on the other end.