Actually, the coolant is circulated throughout the engine whenever the water pump turns. The thermostat only lets it out to cool off in the radiator. If you have an oil cooler, then the bypass hose is needed to provide flow to it. There is a second port on the intake that supplies hot coolant to the heater. If you're not running an oil cooler, or a heater, then you can build an intake manifold that goes without these provisions... otherwise, I'd keep the design similar to the stock cooling scheme.
http://www.mazdatrucking.com/B2200/B22CoolantFlow.html