The Mayor
+1y
Definitetly need to run a smaller overall diameter tire. I'm currently running a McGaughy's 4/6 kit and the stock size tire touches the fender lip on the front. The tires I have (275/45R20) are just small enough to not touch during articulation. If you are going to run a 5/7 drop, you might need to run a slightly smaller tire yet. Best bet would be to install the kit, then take your measurements before buying your tires.
That is really the only issue on a static drop. Otherwise just make sure you check your pinion angle and get an alignment. Double check the tourque more often than you might think. I have gone through two driveshafts because the rear u-bolts kept coming loose, even after checking them three times over the span of about 2000 miles. Shit happens, be proactive.
If you have new front spindles, don't forget the threadlocker!